PatchSiren cyber security CVE debrief
CVE-2025-27578 Pixmeo CVE debrief
CVE-2025-27578 affects Pixmeo OsiriX MD and was published by CISA on 2025-05-08. The advisory says a crafted DICOM file can trigger a use-after-free condition, leading to memory corruption and a denial-of-service impact. The issue is scored CVSS 7.5 (HIGH) with availability impact only. Pixmeo recommends updating to the latest version of OsiriX MD.
- Vendor
- Pixmeo
- Product
- OsiriX MD
- CVSS
- HIGH 7.5
- CISA KEV
- Not listed in stored evidence
- Original CVE published
- 2025-05-08
- Original CVE updated
- 2025-05-08
- Advisory published
- 2025-05-08
- Advisory updated
- 2025-05-08
Who should care
Hospitals, clinics, and imaging teams that use Pixmeo OsiriX MD; endpoint and application security teams responsible for medical imaging software; and IT staff managing DICOM upload workflows or systems exposed to untrusted file intake.
Technical summary
The source advisory describes a use-after-free vulnerability in OsiriX MD. An attacker who can upload a crafted DICOM file may trigger memory corruption and crash the application, causing denial of service. The supplied CVSS v3.1 vector is AV:N/AC:L/PR:N/UI:N/S:U/C:N/I:N/A:H, indicating a network-reachable attack with no privileges or user interaction required and high availability impact.
Defensive priority
High
Recommended defensive actions
- Install the latest version of OsiriX MD from Pixmeo as soon as possible.
- Inventory all OsiriX MD deployments and confirm which systems are exposed to DICOM file uploads or other untrusted input paths.
- Limit access to DICOM upload and ingestion workflows to trusted users and trusted network segments where feasible.
- Monitor for crashes, memory faults, or repeated service restarts in affected imaging workflows.
- Contact Pixmeo directly if you need vendor support or clarification about remediation.
Evidence notes
Primary facts come from the CISA CSAF advisory for CVE-2025-27578 and its associated references. The advisory states the flaw is a use-after-free that can be triggered by a crafted DICOM file, causing memory corruption and denial of service. The advisory also provides the vendor remediation to download the latest version of OsiriX MD. The CVE and advisory were published and last modified on 2025-05-08; no KEV entry was provided in the supplied corpus.
Sources and references
Verified primary and authoritative sources
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CVE-2025-27578 CVE Program record
Publisher, destination, and source semantics verified
URL: https://www.cve.org/CVERecord?id=CVE-2025-27578
CVE Program - Official CVE Program record with source-provided CVE metadata.
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CVE-2025-27578 NVD vulnerability detail
Publisher, destination, and source semantics verified
URL: https://nvd.nist.gov/vuln/detail/CVE-2025-27578
NIST National Vulnerability Database - Official NIST NVD detail page and source-specific vulnerability assessment.
Supplemental references
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Source item URL
Unverified legacy reference
URL: https://raw.githubusercontent.com/cisagov/CSAF/develop/csaf_files/OT/white/2025/icsma-25-128-01.json
cisa_csaf
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Source reference
Unverified legacy reference
URL: https://www.cisa.gov/news-events/ics-medical-advisories/icsma-25-128-01
Reference
-
Source reference
Unverified legacy reference
URL: https://www.cisa.gov/uscert/ics/alerts/ICS-ALERT-10-301-01
Reference
-
Source reference
Unverified legacy reference
URL: https://www.cisa.gov/resources-tools/resources/ics-recommended-practices
Reference
-
Source reference
Unverified legacy reference
URL: https://www.cisa.gov/sites/default/files/publications/Cybersecurity_Best_Practices_for_Industrial_Control_Systems.pdf
Reference
-
Source reference
Unverified legacy reference
URL: https://www.cisa.gov/topics/industrial-control-systems
Reference
-
Source reference
Unverified legacy reference
URL: https://www.cisa.gov/uscert/sites/default/files/publications/emailscams0905.pdf
Reference
-
Source reference
Unverified legacy reference
URL: https://www.cisa.gov/uscert/ncas/tips/ST04-014
Reference
Methodology and review provenance
AI-assisted synthesis based on stored public vulnerability evidence. System validation, approval state, and publication status do not by themselves establish human review of this revision. PatchSiren helps prioritize defensive review and does not prove exposure or remediation on any system.